Most recents publications :
- Replication confers β cell immaturity (Puri et al. Nature Communications 2018)
- All mixed up: defining roles for β-cell subtypes in mature islets (Liu et al. Genes & Development 2017)
- Designing β Cells (Hebrok Cell Metabolism 2017)
- PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance (Roy et al. Genes & Development 2016)
- Regulation of Cellular Identity in Cancer (Roy et al. Dev Cell 2015)
- Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation. (Russ et al., Stem Cells Int. 2016)
- Islet formation in mice and men: lessons for the generation of functional insulin-producing β-cells from human pluripotent stem cells. (Nair et al. Curr Opin Genet Dev 2015)
- Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro (Russ et al., EMBO J 2015)
- Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation (Roy et al., Genes Dev 2015)
- Plasticity and Dedifferentiation within the Pancreas: Development, Homeostasis, and Disease (Puri et al., Cell Stem Cell 2015)
- Taming the young and restless-epigenetic gene regulation in pancreas and beta-cell precursors (Russ and Hebrok, EMBO J 2014)
- Aberrant innate immune activation following tissue injury impairs pancreatic regeneration (Folias et al., PLoS One 2014)
- Dicer regulates differentiation and viability during mouse pancreatic cancer initiation (Morris et al., PLoS One 2014)
- Diabetes: Solving human β-cell development-what does the mouse say? (Folias and Hebrok, Nat Rev Endocrinol 2014)
- The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma (von Figura et al., Nat Cell Bio 2014)
- VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus (Puri et al., Genes Dev 2013)
- Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice (Puri et al., PLoS One 2013)
- Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar-to-ductal metaplasia (Greer et al., Gastroenterology 2013)
- Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development (Parent et al., Cell Stem Cell 2013)
- Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation (von Figura et al., Gut 2013)
- Factors Expressed by Murine Embryonic Pancreatic Mesenchyme Enhance Generation of Insulin-Producing Cells From hESCs (Guo et al., Diabetes 2013)
- Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma (von Figura et al., Cancer Cell 2012)
- Bmi1 is required for regeneration of the exocrine pancreas in mice (Fukuda et al., Gastroenterology 2012)
- Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice (Landsman et al., PNAS 2011)
- Pancreatic mesenchyme regulates epithelial organogenesis throughout development (Landsman et al., PLoS Biol 2011)
- Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression (Fukuda et al., Cancer Cell 2011)
- Primary cilia regulate Gli/Hedgehog activation in pancreas (Cervantes et al., PNAS 2010)
- Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function (Lau and Hebrok, Diabetes 2010)
- Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice (Morris et al., J Clin Invest 2010)